Ioannis Pavlidis graduated from the Department of Biological Applications and Technologies of the University of Ioannina, Greece (2005). In 2011 he was awarded his PhD from the same Department. The PhD thesis was focusing on the study of the structure and the function of hydrolytic enzymes in nanostructured systems. In 2013 he also graduated from the Department of Primary Education of the University of Ioannina.
From 2011 to 2015 he worked as postdoctoral researcher at the Department of Biotechnology and Enzyme Catalysis, Institute of Biochemistry, University of Kassel (Germany). From 2015 until 2017 he worked as a group leader in the Department of Biochemistry, Institute of Biology, University of Kassel (Germany), where he established the group of Biotechnology. In 2017 he was elected as Assistant Professor at the Department of Chemistry, University of Crete and he took up duty in 2018.
His research focuses on the fields of Enzyme Technology & Applied Biocatalysis. He is mostly active on:
- Identification of novel enzymes and metabolic pathways
- Development of enzymatic cascades.
- Biocatalysts optimization via protein engineering.
- Rational design of enzymes using bioinformatic analysis.
- Valorization of wastes via biocatalytic processes.
- Development of industrially relevant bioprocesses.
• A. Su, T. Tyrikos-Ergas, A.N. Shirke, Y. Zou, A. Dooley, I.V. Pavlidis*, R.A. Gross R.A. Gross (2018) Revealing cutinases’ capabilities as enantioselective catalysts. ACS Catalysis, 8: 7944-7951.
• L.L. Kailing, D. Bertinetti, C.E. Paul, T. Manszewski, M. Jaskolski, F.W. Herberg, I.V. Pavlidis* (2018) S-Adenosyl-L-homocysteine hydrolase inhibition by a synthetic nicotinamide cofactor biomimetic. Frontiers in Microbiology, 9: 505
• A.W.H. Dawood, M.S. Weiß, C. Schulz, I.V. Pavlidis, H. Iding, R.O.M.A. de Souza, U.T. Bornscheuer (2018) Isopropylamine as amine donor in transaminase-catalyzed reactions: Better acceptance through reaction and enzyme engineering. ChemCatChem, DOI:10.1002/cctc.201800936 (Hot Topic: Biocatalysis).
• L.L. Kailing, D. Bertinetti, F.W. Herberg, I.V. Pavlidis* (2017) A coupled photometric assay for characterization of S-adenosyl-L-homocysteine hydrolases in the physiological hydrolytic direction. New Biotechnology, 39: 11-17.
• I.V. Pavlidis, M.S. Weiß, M. Genz, P. Spurr, S.P. Hanlon, B. Wirz, H. Iding, U.T. Bornscheuer (2016) Identification of (S)-selective transaminases for the asymmetric synthesis of bulky chiral amines. Nature Chemistry, 8(11): 1076-1082.