Our Approach

we have a strong focus on synthetic organic chemistry and
the basic tool of our strategy are Multi-Component Reactions (MCRs)

Our Chemistry provides:

Diversity and Convergence
Complexity generation
Time/resourse saving
Easiness of performance
  1. Expanding the chemical space - we discover new Multi-Component reactions employing different building blocks based on their different functionalities. Our target; Novel scaffolds, libraries ready to be screened
  2. Molecule Functionalization via MCRs (1) - we offer alternative and more efficient synthetic pathways towards molecules of interest; pharmaceuticals and agrochemicals
  3. Molecule Functionalization via MCRs (2) - we target unprecedented organic materials

Our Awesome Team

Dr Constantinos Neochoritis

Assistant Professor

Xiaofang Lei

PhD student

Michalis Fragiadakis

PhD student

Maria Thomaidi

PhD student

Paria Anastasiou 

MSc student

Konstantinos Adamis

MSc student

Marios Zingiridis

MSc student

Aliki Fotiadi

MSc student

Eirini Fotopoulou

Postdoctoral researcher

Alexandros Vasilakis

BSc student

Giannis Volyrakis

BSc student

Recent Publications

 M. Fragkiadakis, C. G. Neochoritis, Synlett 2022, 33, 1913-1926.
2. M. Fragkiadakis, M. Zingiridis, E. Loukopoulos, C. G. Neochoritis, Mol.Divers. 2022, in press.
3. X. Lei, G. K. Angeli, C. G. Neochoritis, A. Dömling, Green Chem. 2022, 24, 6168-6171.
4. M. Thomaidi, L. Vagiaki, N. P. Tripolitsiotis, G. K. Angeli, T. Zarganes-Tzitzikas, K. Sidiropoulou, C. G. Neochoritis, ChemMedChem 2022, 17, e202200246.
5. X. Lei, G. K. Angeli, A. Dömling, C. G. Neochoritis, Eur. J. Org. Chem. 2022, 20, e202200220.
6.  X. Lei, M. Thomaidi, G. K. Angeli, A. Dömling, C. G. Neochoritis, Synlett 2022, 33, 155-160.
7. X. Lei, P. Lampiri, P. Patil, G. Angeli, C. G. Neochoritis, A. Dömling, ChemComm 2021, 57, 6652-6655.
8. N. Griboura, K. Gatzonas, C. G. Neochoritis, Chemmedchem 2021, 16, 1997-2020.
9. N. Tripolitsiotis, M. Thomaidi, C. G. Neochoritis, Eur. J. Org. Chem. 2020, 6525-6554.
10. F. Sutanto, S. Shaabani, C. G. Neochoritis, T. Zarganes-Tzitzikas, P. Patil, E. Ghonchepour, A. Dömling, Science Advances 2021, 7, eabd9307.

Our Latest News

The latest news, results and ongoing stuff of our group



X. Lei published her fourth article in the prestigious Green Chemistry which has been nominated as hot article 2022! 
Well done Xiaofang!!



M. Fragkiadakis, published two articles (in press), accessing new modalities! Well done Michalis!


Academy of Athens

Prof Neochoritis has been awarded by the Academy of Athens, “Hildegard, widow of Leonidas Zervas award” for groundbreaking research in organic chemistry {10.1039/D1CC02384E}




Chemistry department, University of Crete, Heraklion, Greece





We are always looking for enthousiastic researchers from around the world!

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