Our Approach

we have a strong focus on synthetic organic chemistry and
the basic tool of our strategy are Multi-Component Reactions (MCRs)

Our Chemistry provides:

Diversity and Convergence
Complexity generation
Time/resourse saving
Easiness of performance
  1. Expanding the chemical space - we discover new Multi-Component reactions employing different building blocks based on their different functionalities. Our target; Novel scaffolds, libraries ready to be screened
  2. Molecule Functionalization via MCRs (1) - we offer alternative and more efficient synthetic pathways towards molecules of interest; pharmaceuticals and agrochemicals
  3. Molecule Functionalization via MCRs (2) - we target unprecedented organic materials

Our Awesome Team

Dr Constantinos Neochoritis

Associate Professor

Michalis Fragiadakis

Postdoctoral researcher

Paria Anastasiou

MSc student

Marios Zingiridis

MSc student

Michail Georgoulakis

MSc student

Danai Papachristodoulou

BSc student

Stelios Polychroniadis

BSc student

past members

1. Konstantinos Gatzonas
2. Nefeli Griboura
3. Nikolaos Tripolitsiotis
4. Panagiota Lampiri
5. Maria Gaidatzi
6. Zoi Kardasi
7. Eleftheria Chatziorfanou
8. Michail Georgoulakis
9. Christina Tomza
10. Alexandros Vasilakis
11. Ioannis Volyrakis
12. Despoina Menegaki
13. Ioanna Petritaki 

1. Aliki Fotiadi
2. Maria Thomaidi
3. Konstantinos Adamis 

1. Xiaofang Lei
2. Michalis Fragiadakis

1. Eirini Fotopoulou


Recent Publications

M. Fragkiadakis, P.K Anastasiou, I. Volyrakis, A. Pantousas, C.C. Stoumpos, C.G. Neochoritis, ChemComm 2023, 59, 14411-14414.
2. M. Fragkiadakis, P.K. Anastasiou, M. Zingiridis, M.E. Triantafyllou-Rundell, A. Reyes Romero, C. C. Stoumpos, C. G. Neochoritis, J. Org. Chem. 2023, 88, 12709-12715. 
. E. Fotopoulou, M. Fragkiadakis, C. G. Neochoritis, Tet Lett 2023, 120, 154453.
4. M. Fragkiadakis, C. G. Neochoritis, Synlett 2022, 33, 1913-1926.
5. M. Fragkiadakis, M. Zingiridis, E. Loukopoulos, C. G. Neochoritis, Mol.Divers. 2022, 10.1007/s11030-022-10502-9.
6. X. Lei, G. K. Angeli, C. G. Neochoritis, A. Dömling, Green Chem. 2022, 24, 6168-6171.
7. M. Thomaidi, L. Vagiaki, N. P. Tripolitsiotis, G. K. Angeli, T. Zarganes-Tzitzikas, K. Sidiropoulou, C. G. Neochoritis, ChemMedChem 2022, 17, e202200246.
8. X. Lei, G. K. Angeli, A. Dömling, C. G. Neochoritis, Eur. J. Org. Chem. 2022, 20, e202200220.
9.  X. Lei, M. Thomaidi, G. K. Angeli, A. Dömling, C. G. Neochoritis, Synlett 2022, 33, 155-160.
10. X. Lei, P. Lampiri, P. Patil, G. Angeli, C. G. Neochoritis, A. Dömling, ChemComm 2021, 57, 6652-6655.
11. N. Griboura, K. Gatzonas, C. G. Neochoritis, Chemmedchem 2021, 16, 1997-2020.
12. N. Tripolitsiotis, M. Thomaidi, C. G. Neochoritis, Eur. J. Org. Chem. 2020, 6525-6554.

Our Latest News

The latest news, results and ongoing stuff of our group



Our group participated on the 1st Aristotle Conference on Chemistry with 5 posters, 1 invited talk and 2 awards!!


EurJOC AGC Award

Prof Neochoritis has been awarded by the EurJOC for the best paper published in 2022 in Greece!


Chatzimarinaki Award

Mr Fragkiadakis defended very successfully his PhD. This is the second one from our group! Congrats Michalis!




Chemistry department, University of Crete, Heraklion, Greece





We are always looking for enthousiastic researchers from around the world!

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