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Our Approach

we have a strong focus on synthetic organic chemistry and
the basic tool of our strategy are Multi-Component Reactions (MCRs)

Our Chemistry provides:

More about MCR chemistry
Diversity and Convergence
Complexity generation
Time/resourse saving
Easiness of performance
  1. Expanding the chemical space - we discover new multicomponent reactions employing different building blocks based on their different functionalities. Our target; Novel scaffolds, libraries ready to be screened against any target
  2. Drug Discovery - we offer alternative and more efficient synthetic pathways towards molecules of interest; generics, agrochemicals, design (cheminformatics, docking) and extensive SARs
  3. New Modalities - we target unprecedented scaffolds, macrocycles, glues, 3D molecules

Our Awesome Team

Dr Constantinos Neochoritis

Associate Professor

Michail Georgoulakis

MSc student

Maritina Giannakaki

MSc student

Michail Kapsalis

MSc student

Danae Papachristodoulou

MSc student

Konstantina Nikovia

MSc student

Foteini Kakari

BSc student

Iakovos Konstantaras

BSc student

past members

1. Konstantinos Gatzonas
2. Nefeli Griboura
3. Nikolaos Tripolitsiotis
4. Panagiota Lampiri
5. Maria Gaidatzi
6. Zoi Kardasi
7. Eleftheria Chatziorfanou
8. Michail Georgoulakis
9. Christina Tomza
10. Alexandros Vasilakis
11. Ioannis Volyrakis
12. Despoina Menegaki
13. Ioanna Petritaki
14. Danae Papachristodoulou
15. Stylianos Polychroniadis
16. Stavroula Xyrafaki
17. Despoina Kantartzoglou

1. Aliki Fotiadi
2. Maria Thomaidi
3. Konstantinos Adamis
4. Marios Zingiridis
5. Paria Anastasiou

1. Xiaofang Lei
2. Michalis Fragiadakis

1. Eirini Fotopoulou
2. Michalis Fragiadakis

Mobirise

Recent selected publications


1. K. S. Adamis, M. Georgoulakis, I. Angelonidis, D. Korovesis, C. Papadopoulos, M. Kapsalis, N. Tavernarakis, N. Eleftheriadis,* C. G. Neochoritis*, ChemAEurJ 2025, in press.
2. M. Fragkiadakis, T. Stergiannakos, N. D. Charistos, A. G. Papadopoulos, C. C. Stoumpos, C. G. Neochoritis, EurJOC 2025, e202500212.
3. P.K Anastasiou, M. Fragkiadakis, M. Thomaidi, K.G. Froudas, C. G. Neochoritis, OrgLett 2025, 27, 1829-1834.
4 M. Zingiridis, D. Papachristodoulou, D. Menegaki, K.G. Froudas, C.G. Neochoritis, BJOC 2025, 21, 217-225.
5. M. Fragkiadakis, M. Thomaidi, T. Stergiannakos, E. Chatziorfanou, M. Gaidatzi, A. Barakat, C. Stoumpos, C.G. Neochoritis ChemAEurJ 2024, 30, e202401461.
6. M. Fragkiadakis, E. Fotopoulou, K.G. Froudas, C.G. Neochoritis EurJOC 2024, 27, e202400581.
7. E. Fotopoulou, P.K. Anastasiou, C. Tomza, C.G. Neochoritis Tetrahedron Green Chem 2024, 3, 100044.
8. E. Fotopoulou, A. Vasilakis, C. G. Neochoritis Synlett 2024, 35, A-E.
9. M. Fragkiadakis, M. Zingiridis, E. Loukopoulos, C. G. Neochoritis, Mol.Divers. 2024, 28, 29-35.
10. M. Fragkiadakis, P.K Anastasiou, I. Volyrakis, A. Pantousas, C.C. Stoumpos, C.G. Neochoritis, ChemComm 2023, 59, 14411-14414.
11. M. Fragkiadakis, P.K. Anastasiou, M. Zingiridis, M.E. Triantafyllou-Rundell, A. Reyes Romero, C. C. Stoumpos, C. G. Neochoritis, J. Org. Chem. 2023, 88, 12709-12715.

Our Latest News

The latest news, results and ongoing stuff of our group

Mobirise

Hellenic Symposium on Medicinal Chemistry

Our group succesfully participated in the 20th Hellenic Symposium on Medicinal Chemistry on the 3-5/4/2025 !

Mobirise

CSC 2025

Prof Neochoritis has been selected to represent EuChemS by presenting his work on the Young Investigators Workshop 2025 in Ottawa, Canada!

Mobirise

Publication

We were able to evolve fluorescein from a simple imaging agent to a potent theranostic. Check our EDI strategy: 10.1002/chem.202501513

funding...

HFRI

Hellenic Foundation of
Research & Innovation ELKE@UoC TelesisPharma Empirikion Idryma

find out more...

Principle
Investigator MACRO Scopus Our lab
Mobirise

Contact

Address:

Chemistry department, University of Crete, Heraklion, Greece

Phone:

+302810545024

E-mail:

kneochor@uoc.gr


We are always looking for enthousiastic researchers from around the world!

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