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Associate Professor George Vassilikogiannakis web: http://www.chemistry.uoc.gr/organic |
Research InterestsBrief Biography
Georgios Vassilikogiannakis obtained his Ph.D in 1998 from the University of Crete (Greece). His doctoral studies focused on electrophilic additions to fullerenes and were conducted in the laboratories of Professor M. Orfanopoulos. From 1999 to 2002 he was a postdoctoral fellow at The Scripps Research Institute (San Diego, California) in the group of Professor K. C. Nicolaou. Here he participated in the completion of a number of natural product total syntheses and in the development of several new synthetic methodologies. He then returned to Crete to begin his independent career in 2002 as an Assistant Professor. In 2006 he received a tenure track position and in 2008 he was promoted to the rank of Associate Professor. Today, the focus of work emanating from his laboratory is the development of new strategies for the synthesis of bioactive natural products. Author or coauthor of 45 scientific articles.
Representative Publications
1. Vassilikogiannakis, G.; Stratakis M. Angewandte Chem. Int. Ed. 2003, 42, 5465 – 5468. “Biomimetic total synthesis of Litseaverticillols A, C, D, F, and G: Singlet-oxygen initiated cascades”
2. Vassilikogiannakis, G.; Margaros, Ι.; Tofi, M. Organic Lett. 2004, 2, 205 – 208. “Olefin metathesis: Remote substituents governing the stereoselectivity of 11-membered-ring formation”
3. Vassilikogiannakis, G.; Margaros, Ι.; Montagnon, T. Organic Lett. 2004, 6, 2039 – 2042. “Biomimetic total synthesis of Litseaverticillols B, E, I, and J and structural reassignment of Litseaverticillol E”
4. Sofikiti, N.; Tofi, M.; Montagnon, T.; Vassilikogiannakis G.; Stratakis M. Organic Lett. 2005, 7, 2357 – 2359. “Synthesis of the spirocyclic core of the Prunolides using a singlet oxygen-mediated sequence”
5. Vassilikogiannakis, G.; Margaros, I.; Montagnon, T.; Stratakis, M. Chemistry a European Journal 2005, 11, 5899 – 5907. “Illustrating the power of singlet oxygen chemistry in a synthetic context: Biomimetic syntheses of litseaverticillols A – G, I and J and the structural reassignment of Litseaverticillol E”
6. Tofi, M.; Georgiou, T.; Montagnon, T.; Vassilikogiannakis G. Organic Lett. 2005, 7, 3347 – 3350. “Regioselective ortho lithiation of 3-aryl and 3-styryl furans”
7. Margaros, I.; Montagnon, T.; Tofi, M.; Pavlakos, E.; Vassilikogiannakis, G. Tetrahedron, 2006, 62, 5308 – 5317. “The power of singlet oxygen chemistry in biomimetic syntheses”
8. Georgiou, T.; Tofi, M.; Montagnon, T.; Vassilikogiannakis, G. Organic Lett. 2006, 8, 1945 – 1948. “A versatile and general one-pot method for synthesizing bis-spiroketal motifs”
9. Tofi, M.; Montagnon, T.; Georgiou, T.; Vassilikogiannakis, G. Org. Biomol. Chem. 2007, 5, 772 – 777. “Using singlet oxygen to synthesize a [6,6,5]-bis-spiroketal in one-pot from a simple 2,5-disubstituted furan”
10. Margaros, I.; Vassilikogiannakis, G. J. Org. Chem. 2007, 72, 4826 – 4831. ”Synthesis of Chinensines A – E”
11. Margaros, I.; Montagnon, T.; Vassilikogiannakis, G. Organic Lett. 2007, 9, 5585 – 5588. ”Spiroperoxy lactones from furans in one pot: Synthesis of (+)-Premnalane A”
12. Margaros, I.; Vassilikogiannakis G. J. Org. Chem. 2008, 73, 2021 – 2023. “Synthesis of (+)-Zerumin B using a regioselective singlet oxygen furan oxidation”
13. Montagnon, T.; Tofi, M.; Vassilikogiannakis G. Acc. Chem. Res. 2008, 41, 1001 – 1011. “Using singlet oxygen to synthesize polyoxygenated natural products from furans”
14. Alberti, M.; Vassilikogiannakis G.; Orfanopoulos M. Organic Lett. 2008, 10, 3997 – 4000. “Stereochemistry of the singlet oxygenation of simple alkenes: A stereospecific transformation”
15. Tofi, M.; Koltsida, K.; Vassilikogiannakis, G. Organic Lett. 2009, 11, 313 – 316. “Singlet-oxygen-mediated one-pot synthesis of 3-keto-tetrahydrofurans from 2-(-hydroxyalkyl) furans”
16. Pavlakos, E. Georgiou, T.; Tofi, M.; Montagnon, T.; Vassilikogiannakis, G. Organic Lett. 2009, ASAP. “γ-Spiroketal γ-lactones from 2-(γ-hydroxyalkyl)furans: Syntheses of epi-pyrenolides D and crassalactone D”